A comparative study of combination octreotide plus methylprednisolone with octreotide and placebo on prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)pancreatitis

Δείτε το αρχείο http://www.annalsgastro.gr/index.php/annalsgastro/article/view/40  
Φορέας Ελληνική Γαστροεντερολογική Εταιρία
Συλλογή Annals of Gastroenterology A comparative study of combination octreotide plus methylprednisolone with octreotide and placebo on prevention of post-endoscopic retrograde cholangiopancreatography
(ERCP)pancreatitis
Επιμέρους συλλογή Original Articles
ΠεριγραφήSUMMARY This study compares the effect of the combination of octreotide plus methylprednisolone with octreotide and placebo on biochemical and clinical parameters of endoscopic retrograde cholangiopancreatograpy (ERCP) induced pancreatitis. Two hundred and twenty two patients were randomised to receive either octreotide plus methylprednisolone, octreotide or placebo. There was no difference in the median serum amylase at 2 to 24 hours after ERCP in the three groups. Clinical pancreatitis, developed in 11 patients -one in the octretode plus methylprednisolone, four in the octretode and six in the placebo groups, although there was no statistically significant difference between the three groups. This study suggests a tendency that octreotide plus methylprednisolone may protect against ERCP- induced pancreatitis. Key words: Octreotide, Methylprednisolone, Hyperamylasemia, Pancreatitis, Endoscopic Retrograde Cholangiopancreatography. Abbreviations: Endoscopic Retrograde Cholangiopancreatography (ERCP), Endoscopic Sphincterotomy (ES)
Δημιουργοί Pilpilidis I., Vasiliadis Th., Joseph Ch., Kalomenopoulou M., Katsinelos P., . Christodoulou K., . Katsiba D., Xiarchos P.,
ΕκδότηςAnnals of Gastroenterology
Ημερομηνία2007-03-19
Μορφότυποςapplication/pdf
ΠηγήAnnals of Gastroenterology; Volume 13, No 4 (2000)