Comparison of current alkylating agents with a homo-aza-steroidal ester for antineoplastic activity

 
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Comparison of current alkylating agents with a homo-aza-steroidal ester for antineoplastic activity

Mourelatos, Dionysios
Mioglou-Kalouptsi, Eleftheria
Catsoulacos, P.
Papageorgiou, Athanasios
Margarity, E.

The modified steroidal alkylating agent, 17 beta-hydroxy-3-aza-A-homo-4 alpha-androsten-4-one-pbis(2-chloroethyl)aminophenoxyacetate has been tested against L1210 and P388 leukemias, and Lewis lung cancer, on DNA synthesis of EAT, L1210, P388, and BHK cell cultures, and on the induction of sister chromatid exchange. Comparable studies in vivo and in vitro were also done with p-bis(2-chloroethyl)aminophenoxyacetic acid, cyclophosphamide, melphalan, and chlorambucil.

Article / Άρθρο
info:eu-repo/semantics/article

Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (EL)
Aristotle University of Thessaloniki (EN)

Αγγλική γλώσσα

1994
2009-07-17T09:36:57Z


Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Σχολή Επιστημών Υγείας, Τμήμα Ιατρικής

urn:ISSN:00302414
Oncology, vol.51 [1994] p.74-78 [Published Version]

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info:eu-repo/semantics/openAccess



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