Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms

 
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Late-life Depression and Alzheimer Disease: A Potential Synergy of the Underlying Mechanisms

Aliev, Gjumrakch
Ashraf, Ghulam Md
Michmizos,Dimitrios
Tarasov, Vadim V.
Leszek, Jerzy
Trypka, Elżbieta
Koutsouraki, Effrosyni
Yarla, Nagendra Sastry

A number of biological and clinical characteristics typical of late life depression (LLD) have been suggested by recent research findings. The close association of LLD with cognitive impairment is now well documented and evidenced. However, it is still not clear whether it is depression that leads to cognitive decline, and in more severe cases, to dementia. The work presented in this review article suggests that depression and dementia frequently and strongly copresent, even if the causality remains largely opaque.

Article / Άρθρο
info:eu-repo/semantics/article

Aging, Alzheimer disease, Depression, Dementia, BDNF

Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (EL)
Aristotle University of Thessaloniki (EN)

Αγγλική γλώσσα

2016-11-07T19:52:50Z
2016


Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Σχολή Επιστημών Υγείας, Τμήμα Ιατρικής

Current Medicinal Chemistry, no.23 [2016] p.1-6

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info:eu-repo/semantics/openAccess



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