Advances in the treatment of Helicobacter pylori infection in children

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Advances in the treatment of Helicobacter pylori infection in children (EN)

Bontems, Patrick
Kalach, Nicolas; Saint Antoine Pedatric Clinic, Hôpital Saint Vincent de Paul, Groupement des Hôpitaux de l’Institut Catholique de Lille (GHICL), Faculté de Médecine & Maïeutique, Lille-France
Cadranel, Samy

In this review we elaborate on two main questions concerning the management of Helicobacter pylori infection in children. First, we focus on who should be treated. In the presence of Helicobacter pylori (H. pylori)-associated peptic ulcer disease, eradication of the micro-organism is recommended. When H. pylori infection is detected by biopsy-based methods in the absence of peptic ulcer disease in a child with dyspeptic symptoms, treatment of H. pylori infection may be considered. In infected children whose first degree relatives have gastric cancer, treatment can be offered. A ‘test-and-treat’ strategy is not and has never been recommended in children. The second issue to address is what the recommended treatments are. ESPGHAN/NASPGHAN recommends that treatment tailored to susceptibility testing should be the first choice in pediatric patients. The duration of therapy should be 10-14 days. Costs, compliance and adverse effects should be taken into account. Checking the result of eradication with a reliable non-invasive test such as the 13C urea breath test, is recommended at least 4-8 weeks following completion of therapy.Keywords Helicobacter pylori, treatment, childAnn Gastroenterol 2015; 28 (1): 10-18 (EN)

Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Gastroenterologiki Company (EN)

2015-01-05


Annals of Gastroenterology (EN)

Annals of Gastroenterology; Volume 28, No 1 (2015); 10 (EN)



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