Colonoscopy outcome, safety and efficacy of colon cleansing in chronic renal failure

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2007 (EN)
Colonoscopy outcome, safety and efficacy of colon cleansing in chronic renal failure (EN)

E.V. Tsianos, H. Pappas, K.C. Siamopoulos,
Margarita Economou, Marina Rizou, Ioanna Theodorou,, K.H. Katsanos, D.K. Christodoulou,

SUMMARY Objectives: We investigated the effectiveness and safety of three different methods of colon cleansing and we also recorded the outcome and findings of lower gastrointestinal tract endoscopy in patients with chronic renal failure. Methods: We prospectively collected 39 patients with chronic renal failure The patients who were referred for endoscopy were randomly given one of the following: For colonoscopy (a) Method I; liquid diet for three days, enemas with sodium phospate (Fleet) and X-Prep (senna-based laxative), and (b) Method II; gut – irrigation with a commercially available polyethylene glycol and electrolytes solution. For sigmoidoscopy (c) Method III; enemas with sodium phosphate (Fleet). A gastroenterologist graded the cleanliness of the segments of colon during endoscopy. Safety profile including renal function and electrolytes were recorded prior to preparation and prior to endoscopy for each patient. In addition, patient acceptance of bowel preparation methods (tolerance) was recorded, including any symptoms of discomfort. Results: We found that among cleansing methods, method I and II were equally effective. Method III had a good cleansing effect on the rectosigmoid (10/12) but only fair cleansing effect on the descending colon (6/12). The tolerance of preparation was similar for all three methods. The safety profile was acceptable for all three methods. Twelve out of 39 patients had at least one positive endoscopic finding Conclusions: Colon cleansing methods are safe for chronic renal failure patients, provided that adequate monitoring of electrolytes and renal function markers is available and an experienced nephrologist is reviewing the patient’s records and current condition. Key words: colonoscopy, colon cleansing, chronic renal failure, hemodialysis, colon preparation, continuous ambulatory peritoneal dialysis (CAPD) (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 16, No 1 (2003) (EN)

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