Quality of life and factors predictive of burden among primary caregivers of chronic liver disease patients


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Quality of life and factors predictive of burden among primary caregivers of chronic liver disease patients (EN)

Morgan, Timothy; VA Long Beach Healthcare System
Ma, Grace; VA Long Beach Healthcare System
Chao, Daniel; University of California-Irvine
Nguyen, Douglas L.; University of California Irvine

none (EN)

Background Chronic liver disease increases the socioeconomic and emotional burden on the patient’s caregiver. This is important because a patient’s adherence to therapy and transplant eligibility is dependent on the caregiver’s ability to handle these challenges.Methods This was a prospective, cross-sectional study of 50 primary caregivers of patients with advanced liver disease. Caregivers completed the RAND 36-item (Short Form [SF-36]) Health Survey and the Zarit Burden Scale survey. Caregiver quality of life, based on the SF-36, was compared using t-tests with the scores of the National reference population as controls.Results In our cohort, the mean age of caregivers was 56.9±11.4 years, 40 (83.3%) were female, and 34 (70.8%) were spouses/significant others of the patient. Compared with the adjusted National norm data, caregivers scored substantially lower in categories of role limitations due to emotional problems (P<0.001), vitality (P=0.025), mental health (P=0.005), and social functioning (P=0.002). While the adjusted physical component score of the caregivers was comparable to the National mean, the mental component score (MCS) was lower than the National average (42.4±13.3 vs. 50.0±10, P<0.001). Though only 8 of 50 (16.0%) subjects reported a formal diagnosis of depression or anxiety, 23 (46.0%) had MCS <42, a strong predictor of clinical depression, based on previous studies.Conclusions Primary caregivers of patients with advanced liver disease have significantly lower SF-36 mental health scores compared with the general population. Comparison of SF-36 scores to caregiver history suggests under recognition of mental health problems in this population.Keywords Chronic liver disease, caregiver burden, depressionAnn Gastroenterol 2015; 28 (1): 124-129 (EN)

Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Gastroenterologiki Company (EN)


Annals of Gastroenterology (EN)

Annals of Gastroenterology; Volume 28, No 1 (2015); 124 (EN)

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