Gut failure in critical care: old school versus new school

 
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2015 (EN)
Gut failure in critical care: old school versus new school (EN)

Pneumatikos, Ioannis
Sertaridou, Eleni
Kolios, George
Papaioannou, Vasilios

The concept of bacterial translocation and gut-origin sepsis as causes of systemic infectious complications and multiple organ deficiency syndrome in surgical and critically ill patients has been a recurring issue over the last decades attracting the scientific interest. Although gastrointestinal dysfunction seemingly arises frequently in intensive care unit patients, it is usually underdiagnosed or underestimated, because the pathophysiology involved is incompletely understood and its exact clinical relevance still remains controversial with an unknown yet probably adverse impact on the patients' outcome. The purpose of this review is to define gut-origin sepsis and related terms, to describe the mechanisms leading to gut-derived complications, and to illustrate the therapeutic options to prevent or limit these untoward processes.Keywords Gut failure, bacterial translocation, selective gut decontamination, immunonutritionAnn Gastroenterol 2015; 28 (3): 307-320 (EN)

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Society of Gastroenterology (EN)

2015-06-11


Hellenic Society of Gastroenterology (EN)

1792-7463
1108-7471
Annals of Gastroenterology; Volume 28, No 3 (2015); 309 (EN)



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