New Trends in Early Detection of Colorectal Cancer

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2007 (EN)
New Trends in Early Detection of Colorectal Cancer (EN)

K. Tsamakidis, E. Paraskevas, D. Dimitroulopoulos, D. Xinopoulos,

SUMMARY Current practice guidelines recommend annual fecal occult blood-test screening for colorectal cancer in the averagerisk population over the age of 50. Efficacy of fecal occult blood-test screening is supported by several recent, controlled, prospective trials and case-control studies. On the other hand, a new generation of fecal tests based on immunocytochemical and RT-PCR methods recently has been developed. There is strong evidence that colon screening of asymptomatic, average-risk subjects can reduce colorectal cancer mortality. Endoscopic screening with sigmoidoscopy can reduce mortality associated with left-sided cancers due to discovery of early curable cancers and the detection and removal of premalignant adenomas. But, with this technique, only the superficial mucosa is visua-lized and at relatively low magnification. Thus, new imaging systems, based on light-tissue interactions, such as optical coherence tomography, light-induced fluorescence spectroscopy, time-resolved fluorescence, light-scattering spectroscopy, chromoendoscopy and magnification endoscopy are being developed to advance endoscopic diagnosis of colorectal cancer. (EN)


Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Society of Gastroenterology (EN)



Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 16, No 3 (2003) (EN)

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