Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO)

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Annals of Gastroenterology
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Clinical practice guidelines for the management of metastatic colorectal cancer: a consensus statement of the Hellenic Society of Medical Oncologists (HeSMO) (EN)

Dervenis, Christos
Makatsoris, Thomas
Agalianos, Christos
Chrysou, Evangelia
Karachaliou, Niki
Athanasiadis, Athanasios
Xynos, Evaghelos
Boukovinas, Ioannis
Pentheroudakis, Georgios
Katopodi, Ourania
Souglakos, John
Triantopoulou, Charina
Kountourakis, Panteleimon
Pechlivanides, George
Ziras, Nikolaos
Papakostas, Pavlos
Androulakis, Nikolaos
Papamichael, Demetris
Tekkis, Paris
Gouvas, Nikolaos
Vassiliou, Vassilis
Georgiou, Panagiotis
Sotiropoulos, George
Xynogalos, Spyridon
Kyriazanos, Ioannis
Tzardi, Maria
Vini, Louiza
Emmanouilidis, Christos
Pilpilidis, Ioannis
Christodoulou, Christos
Sgouros, Joseph

There is discrepancy and failure to adhere to current international guidelines for the management of metastatic colorectal cancer (CRC) in hospitals in Greece and Cyprus. The aim of the present document is to provide a consensus on the multidisciplinary management of metastastic CRC, considering both special characteristics of our Healthcare System and international guidelines. Following discussion and online communication among the members of an executive team chosen by the Hellenic Society of Medical Oncology (HeSMO), a consensus for metastastic CRC disease was developed. Statements were subjected to the Delphi methodology on two voting rounds by invited multidisciplinary international experts on CRC. Statements reaching level of agreement by ≥80% were considered as having achieved large consensus, whereas statements reaching 60-80% moderate consensus. One hundred and nine statements were developed. Ninety experts voted for those statements. The median rate of abstain per statement was 18.5% (range: 0-54%). In the end of the process, all statements achieved a large consensus. The importance of centralization, care by a multidisciplinary team, adherence to guidelines, and personalization is emphasized. R0 resection is the only intervention that may offer substantial improvement in the oncological outcomes.Keywords Colorectal cancer, metastatic disease, surgery, guidelinesAnn Gastroenterol 2016; 29 (4): 390-416 (EN)


Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Society of Gastroenterology (EN)

Αγγλική γλώσσα


Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 29, No 4 (2016); 390 (EN)

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