Ischemic colitis: Clinical, endoscopic and histologic spectrum of 254 cases

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2007 (EN)
Ischemic colitis: Clinical, endoscopic and histologic spectrum of 254 cases (EN)

P. Basioukas, D. Tsantoulas, N. Tamvakis, M. Demonakou, A. Kontogianni, S. Delakidis,

SUMMARY Aim: Ischemic colitis (IC) is generally considered a disease of elderly patients who have associated diseases. It is classified into the non-gangrenous type, and gangrenous type. The aim of this study is to re-evaluate the clinical, endoscopic and histological features of IC in the Greek population. Methodology: We retrospectively analyzed the clinical characteristics, endoscopic and histologic findings in 254 patients (110 men and 144 women) with IC, diagnosed by early endoscopy or surgical management. Results: In non-gangrenous type (percentage: 84%) (127 women, 87 men), the patients´ age range was from 22 to 96 years (mean: 67 years), and 19/214 patients (8.8%) were less than 50 years of age. The clinical features were: melena (54%), abdominal pain (14%) and bloody diarrhea (10%), and the early endoscopy (n=118) showed edema and focal hemorrhage of mucosa (31%). The histological findings were: mucosal atrophy, edema, hyperemia and mild acute inflammation). In gangrenous type (percentage: 16%) (17 women, 23 men), the patients’ age range was from 57 to 89 years (mean: 73 years), and none of the patients were less than 50 years of age. The main symptom was acute abdominal pain (60%), and the histology showed acute ischemic necrosis of the bowel wall in the whole population (100%). Conclusion: IC is a rare disease in the Greek population. The gangrenous type presents only in older patients (>50 years). The non-gangrenous type presents also in younger patients, especially females, and early endoscopy is essential for the accurate diagnosis of disease. Key words: ichemic colitis, colon, clinicopathologic correlation. (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 16, No 4 (2003) (EN)

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