Anesthesia for endoscopic retrograde cholangiopancreatography: target-controlled infusion versus standard volatile anesthesia


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Ελληνική Γαστροεντερολογική Εταιρία
Αποθετήριο :
Annals of Gastroenterology
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Σημασιολογικός εμπλουτισμός/ομογενοποίηση από το EKT

2016 (EL)
Anesthesia for endoscopic retrograde cholangiopancreatography: target-controlled infusion versus standard volatile anesthesia (EN)

Meziane, Mohammed
Drissi Kamili, Noureddine
Ahtil, Redouane
Motiaa, Youssef; Faculty of medicine and pharmacy, Mohamed V. University, Rabat. Morocco Department of anaesthesiology and critical care
Jaafari, Abdelhamid
Bensghir, Mustapha

noone (EN)

Background Endoscopic retrograde cholangiopancreatography (ERCP) is a technique used both for diagnosis and for the treatment of biliary and pancreatic diseases. ERCP has some anesthetic implications and specific complications. The primary outcome aim was to compare two protocols in terms of time of extubation. We also compared anesthetic protocols in terms of hemodynamic and respiratory instability, antispasmodics needs, endoscopist satisfaction, and recovery room stay.Methods Patients were randomized into two groups: standard anesthesia group (Gr: SA) in whom induction was done by propofol, fentanyl and cisatracurium and maintenance was done by a mixture of oxygen, nitrousoxide (50%:50%) and sevoflurane; and intravenous anesthesia group to target concentration (Gr: TCI) in whom induction and maintenance of anesthesia were done with propofol with a target 0.5-2 μg/mL, and remifentanil with a target of 0.75-2 ng/mL.Results 90 patients were included. Extubation time was shorter in Gr: TCI, 15±2.6 vs. 27.4±7.1 min in Gr: SA (P<0.001). The incidence of hypotension was higher in Gr: SA (P=0.009). Satisfaction was better in Gr: TCI (P=0.003). Antispasmodic need was higher in Gr: SA (P=0.023). Six patients in Gr: SA group had desaturation in post-anesthesia care unit (PACU) versus one patient from Gr: TCI (P=0.049). Patients in Gr: TCI had shorter PACU stay 40.2±7.3 vs. 58.7±12.4 min (P<0.001).Conclusion The use of TCI mode allows better optimization of general anesthesia technique during ERCP.Keywords Endoscopic retrograde cholangiopancreatography, general anesthesia, anesthesia intravenous target concentration, complications, time of extubationAnn Gastroenterol 2016; 29 (4): 530-535 (EN)

Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Gastroenterologiki Company (EN)


Annals of Gastroenterology (EN)

Annals of Gastroenterology; Volume 29, No 4 (2016); 530 (EN)

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