Multiple sclerosis and HLA-B27 negative sacroiliitis in a Crohn’s disease patient

This item is provided by the institution :

Repository :
Annals of Gastroenterology
see the original item page
in the repository's web site and access all digital files if the item*

2007 (EN)
Multiple sclerosis and HLA-B27 negative sacroiliitis in a Crohn’s disease patient (EN)

N. Tzambouras, E.V. Tsianos, K.H. Katsanos,

SUMMARY A relationship between inflammatory bowel disease and MS is supported by a higher than expected coexistence of these diseases among families and individuals. A 32 year-old male with Crohn’s disease of the terminal ileum diagnosed 4 years earlier and HLA-B27 bilateral sacroiliitis diagnosed two years earlier, was admitted to our hospital because of an acute episode of blurred vision. In addition the patient complained of urine incontinence. Before this admission the patient had been elsewhere administered three doses of Remicade and 16mg of methylprednisolone p.os. During admission the diagnosis of multiple sclerosis was made (MRI and IgG Index) and Remicade was discontinued. The patient was started on therapy with interferon-beta for MS, oxybutynin hydrochloride (10mg/day) for urine incontinence, prednizolone (10mg/day), methotrexate (10mg/week) and azathioprine (100mg/day) for Crohn’s disease and is now in excellent clinical status. To the best of our knowledge this is one of the very rare cases of Crohn’s disease with HLA-B27 negative sacroiliitis preceding multiple sclerosis diagnosis. Key words: Crohn’s disease, inflammatory bowel disease, ulcerative colitis, multiple sclerosis, Remicade (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 17, No 2 (2004) (EN)

*Institutions are responsible for keeping their URLs functional (digital file, item page in repository site)