Gluten enteropathy: current views on diagnosis and treatment

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2007 (EN)
Gluten enteropathy: current views on diagnosis and treatment (EN)

Panteris, D.G. Karamanolis, V.

Gluten enteropathy, widely known as celiac sprue, is an “old” disease as its basic clinical and pathogenetic features where established 50 years ago. Recently mounting new data have come to light concerning multiple aspects of this disorder. The previously rare clinical entity that presented with a severe chronic diarrheal syndrome following the congestion of certain cereals has changed to a common autoimmune related disease with various manifestations, genetic background and new modes of diagnosis and possible treatment. The contemporary gastroenterologist needs to be aware of all the new “tips and tricks” which will guide his thoughts in suspecting celiac disease and be able to recognize it promptly and reliably. This is clearly important as gluten enteropathy proves itself to be a treatable disease but with insidious and devastating complications if left untreated. In this review an effort has been made to encompass all the recently acquired knowledge concerning the clinical presentation, serologic detection, endoscopic signs, histologic findings and treatment of celiac disease. Keywords: celiac, gluten, treatment, diagnosis, serology, histology, endoscopic markers, refractory sprue (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 18, No 4 (2005) (EN)

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