The epidemiological profile of inflammatory bowel disease in different parts of North-West Greece

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2007 (EN)
The epidemiological profile of inflammatory bowel disease in different parts of North-West Greece (EN)

D. Christodoulou1, A. Kogevinas2, R.F. Logan, E.V. Tsianos1, K.H. Katsanos1,
N.W. Greece IBD, and the

The epidemiological profile of Inflammatory Bowel Disease (IBD) is a topic of great interest because of the differences in incidence, prevalence, sex and age distribution of the disease among countries. North-West Greece (NWG) includes 6 prefectures (Ioannina, Arta, Preveza, Thesprotia, Corfu and Lefkas) and it is an area with a great homogeneity in the population because of its geographical morphology. A retrospective epidemiological study was conducted in this area including all hospitals and private doctors and resulting in the epidemiological registry of 484 patients, the largest in Greece. The peak age is 35-54 years with a very small number of patients under 25 years. Men are more affected than women (2:1) and Corfu patients have the most severe extraintestinal manifestations. The mean annual incidence of IBD in NWG has an approximate 2-fold (1,86) increase from 1992 to 1997 (7,45x 105 Inhabitants) compared with the years 1982-1991 (3,99 x 105 Inhabitants) with Ioannina and Corfu presenting the greatest increase. In addition the gap between ulcerative colitis and Crohn’s disease is decreasing because of Crohn’s more increasing rate. It is also suggested an East-West (Ioannina, Arta, Preveza, Thesprotia, vs Corfu and Lefkas) or an island-mountain profile of IBD is also suggested. Prevalence of IBD is increasing with Ioannina and Corfu presenting the highest numbers and being the most industrialized and tourist regions. This changing profile of Crohn’s disease strengthens the hypothesis that some environmental factor(s), probably in correlation with the genetic factor(s), are responsible for the expression of IBD. Key words: Inflammatory bowel disease, Crohn’s disease, ulcerative colitis, indeterminate colitis, epidemiology, incidence. (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 18, No 4 (2005) (EN)

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