Experimental studies of Peroral Transgastric Abdominal Surgery

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2007 (EN)
Experimental studies of Peroral Transgastric Abdominal Surgery (EN)

P. Koulouris1, C. Kolettas1, S. Chandakas2, M. Sideris3, A. Papalois3, C. Feretis1, D. Kalantzopoulos1,

Background: Recent studies are testing the feasibility of an incisionless endoscopic per-oral approach to the peritoneal cavity in experimental animals. Herein we present our results of peroral peritoneoscopy, liver biopsy, cholecystectomy, fallopian tube and uterus excision, in a porcine model to determine the technical feasibility and safety of Peroral Transgastric Procedures. Methods: The procedures were performed on ten 28-50 Kgr anaesthetised pigs by using sterilized double channel endoscope and catheters. The gastric cavity was irrigated with antibiotic solution and access to the peritoneal cavity was gained after stomach wall incision with needle knife electrocautery. Peritoneoscopy (10 pigs), liver biopsy (1 pig), cholecystectomy (6 pigs) fallopian tube excision (one pig) and Hysterectomy (1 pig) were carried out. Four acute and six survival experiments were performed. Results: All procedures were accomplished successfully. Easily handled complications occurred in two animals. The feasibility of the peroral approach was demonstrated in all acute experiments. In the survival experiments all pigs recovered and thrived during the following four to six weeks.Conclusion: Evidence is given that per-oral transgastric surgery is technically feasible and safe in a porcine model. The method has potential to become an alternative to laparoscopy. Further evaluation in larger series is required. (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 19, No 1 (2006) (EN)

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