A comparative study of combination octreotide plus methylprednisolone with octreotide and placebo on prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)pancreatitis
δείτε την πρωτότυπη σελίδα τεκμηρίου στον ιστότοπο του αποθετηρίου του φορέα για περισσότερες πληροφορίες και για να δείτε όλα τα ψηφιακά αρχεία του τεκμηρίου*
A comparative study of combination octreotide plus methylprednisolone with octreotide and placebo on prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)pancreatitis
(EN)
Kalomenopoulou M.,
Katsiba D.,
Joseph Ch.,
Katsinelos P., .
Pilpilidis I.,
Vasiliadis Th.,
Christodoulou K., .
Xiarchos P.,
SUMMARY
This study compares the effect of the combination of octreotide
plus methylprednisolone with octreotide and placebo
on biochemical and clinical parameters of endoscopic retrograde
cholangiopancreatograpy (ERCP) induced pancreatitis.
Two hundred and twenty two patients were randomised
to receive either octreotide plus methylprednisolone,
octreotide or placebo. There was no difference in the
median serum amylase at 2 to 24 hours after ERCP in the
three groups. Clinical pancreatitis, developed in 11 patients
-one in the octretode plus methylprednisolone, four in the
octretode and six in the placebo groups, although there was
no statistically significant difference between the three
groups. This study suggests a tendency that octreotide plus
methylprednisolone may protect against ERCP- induced
pancreatitis.
Key words: Octreotide, Methylprednisolone, Hyperamylasemia,
Pancreatitis, Endoscopic Retrograde Cholangiopancreatography.
Abbreviations: Endoscopic Retrograde Cholangiopancreatography
(ERCP), Endoscopic Sphincterotomy (ES)
(EN)
Annals of Gastroenterology; Volume 13, No 4 (2000)
(EN)
*Η εύρυθμη και αδιάλειπτη λειτουργία των διαδικτυακών διευθύνσεων των συλλογών (ψηφιακό αρχείο, καρτέλα τεκμηρίου στο αποθετήριο) είναι αποκλειστική ευθύνη των αντίστοιχων Φορέων περιεχομένου.
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