Pregnancy and Crohn’s Disease: Infliximab induction therapy, Accidental Conception, Pregnancy Outcome and Postpartum Complications

 
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2007 (EN)

Pregnancy and Crohn’s Disease: Infliximab induction therapy, Accidental Conception, Pregnancy Outcome and Postpartum Complications (EN)

Tsartsali, Lemonia
Karkatzos, E.
Karantanos, P.
Xirouchakis, E.

Crohn's disease is a well known inflammatory disease of unknown origin. It appears mostly at young ages and the need for a long lasting therapy with immunosuppressing drugs makes decisions about these patients difficult especially when taking into account the need of many female patients to carry out a pregnancy. It is well known that CD exacerbations can provoke adverse effects on the foetus with a great risk of miscarriage. We present a case of a young woman with Crohn's disease under treatment with infliximab who accidentally conceived and was willing to carry out the pregnancy. Since the use of infliximab was not recommended during pregnancy, when the patient presented flare ups she was treated with corticosteroids and 5-ASA in order to achieve remission. The outcome was a spontaneously and successfully terminated pregnancy. During the early post-partum period she also presented a large abdominal cyst that was treated operatively. Key words: Infliximab, inflammatory bowel disease, pregnancy (EN)

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English

2007-04-05


Hellenic Society of Gastroenterology (EN)

1792-7463
1108-7471
Annals of Gastroenterology; Volume 19, No 2 (2006) (EN)




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