Intrahepatic cholestasis associated with giant cell arteritis

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2007 (EN)
Intrahepatic cholestasis associated with giant cell arteritis (EN)

Haritos, D. N.
Boutati, Eleni I.
Papageorgiou, S. G.
Rontogianni, Dimitra
Papadopoulos, A. A.
Economomoulos, Th.

Giant cell arteritis (GCA) is a vasculitis affecting large and medium size arteries and presents mainly in the elderly. Major clinical findings in GCA are headache, visual symptoms, fever and jaw claudication. Laboratory findings include a very high erythrocyte sedimentation rate and anemia. Among other organs that can be affected is the liver. More than 30% of cases exhibit mild elevation of cholestatic enzymes. However, significant elevation of cholestatic enzymes, consistent with primary liver disease is quite rare in GCA A case of a 73-year-old woman with giant cell arteritis, presenting with clinical and laboratory findings suggestive of a primary liver disease is reported. This case is presented to warn physicians that GCA should be included in the differential diagnosis of abnormal liver function tests in the elderly population. Key words: Cholestasis, Giant-cell arteritis, liver dysfunction, (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 19, No 2 (2006) (EN)

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