Serum Pepsinogen I (PGI) and gastrin levels in children with gastritis

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2007 (EN)
Serum Pepsinogen I (PGI) and gastrin levels in children with gastritis (EN)

Panayiotou, Joanna
Roma, Eleftheria
Kafritsa, Yota
Constantopoulos, A.
Barbatis, Calypso
Rokkas, T.
Loutsi, Helen

Background: Studies on the relationship of childhood gastritis with serum PGI and gastrin are few. This prospective study aimed to evaluate their use in the differential diagnosis and assessment of the severity of childhood gastritis. Materials and Methods: Serum PGI and gastrin G-17 (fast-postprandial) were estimated by RIA in 101 symptomatic children, aged 4-16 years (mean 102.7 y) who underwent endoscopy. PGI and gastrin were reevaluated in 14 patients after H pylori eradication. Results: A) 45 children had H pylori gastritis, B) 35 non H. pylori gastritis and C) 21 had non H. pylori normal gastric mucosa. A significant increase of PGI levels (70.9  27.1 ng/ml) was found only in group A, compared to groups B (46.412.9 ng/ml) and C (46.38 11.18 ng/ml p (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 19, No 4 (2006) (EN)

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