Endoluminal fundoplication for the treatment of GERD: A preliminary report of a new transoral approach

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Annals of Gastroenterology
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Endoluminal fundoplication for the treatment of GERD: A preliminary report of a new transoral approach (EN)

Stefanidis, G.
Tsaroucha, Athanasia
Anastasiadou, Evangelia
Karakostas, N.
Marinis, A.
Polydorou, A.

Aim of the study: This is a preliminary report of endoluminal fundoplication (ELF) for the treatment of GERD. Method: Inclusion criteria [age 18-80; BMI < 35; Chronic GERD >6 mo; GERD-health related quality of life score diff ≥ 10 with PPI dependence; DeMeester > 14.7 (after 14 d without PPI); Deteriorated GEV Hill grade ≥ 2 or HH (hiatus hernia) < 2 cm; esophagitis < L.A. (Los Angeles) grade D at time of procedure; acceptable upper GI; acceptable manometry and no visible Barrett's esophagus] are used for enrollment of patients in this protocol. ELF is performed with the use of the EsophyxTM device. Case presentation: Two male patients 37 and 55-years-old with chronic GERD underwent ELF under general anesthesia. Post-procedure period was uneventful and patients were discharged after 24 hours. Cessation of PPIs one week after the procedure was not followed by relapse of GERD symptoms. Conclusion: Current advances in endoscopic treatment of GERD with the development of alternative to surgery endoluminal devices recreating the gastroesophageal valve in a similar pattern as laparoscopic procedures are promising. According to recent studies, reduction of invasiveness, procedural time, adverse effects, hospital stay and need for medical treatment seems to be cost-saving in combination with clinical effectiveness and improved quality of life. (EN)


Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Society of Gastroenterology (EN)

Αγγλική γλώσσα


Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 21, No 2 (2008); 109-113 (EN)

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