Endoluminal fundoplication for the treatment of GERD: A preliminary report of a new transoral approach

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2008 (EN)
Endoluminal fundoplication for the treatment of GERD: A preliminary report of a new transoral approach (EN)

Stefanidis, G.
Tsaroucha, Athanasia
Anastasiadou, Evangelia
Karakostas, N.
Marinis, A.
Polydorou, A.

Aim of the study: This is a preliminary report of endoluminal fundoplication (ELF) for the treatment of GERD. Method: Inclusion criteria [age 18-80; BMI < 35; Chronic GERD >6 mo; GERD-health related quality of life score diff ≥ 10 with PPI dependence; DeMeester > 14.7 (after 14 d without PPI); Deteriorated GEV Hill grade ≥ 2 or HH (hiatus hernia) < 2 cm; esophagitis < L.A. (Los Angeles) grade D at time of procedure; acceptable upper GI; acceptable manometry and no visible Barrett's esophagus] are used for enrollment of patients in this protocol. ELF is performed with the use of the EsophyxTM device. Case presentation: Two male patients 37 and 55-years-old with chronic GERD underwent ELF under general anesthesia. Post-procedure period was uneventful and patients were discharged after 24 hours. Cessation of PPIs one week after the procedure was not followed by relapse of GERD symptoms. Conclusion: Current advances in endoscopic treatment of GERD with the development of alternative to surgery endoluminal devices recreating the gastroesophageal valve in a similar pattern as laparoscopic procedures are promising. According to recent studies, reduction of invasiveness, procedural time, adverse effects, hospital stay and need for medical treatment seems to be cost-saving in combination with clinical effectiveness and improved quality of life. (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 21, No 2 (2008); 109-113 (EN)

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