Idiopathic neonatal hepatitis: a long term follow-up study

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2007 (EN)
Idiopathic neonatal hepatitis: a long term follow-up study (EN)

Karagiozoglou-Lamboudi T.,
Chatziparasidis G.,
Spiroglou K.,
Patsiaura K.,
Xinias J.,
Demertzidou V.,

SUMMARY Background: Idiopathic neonatal hepatitis (INH) is the term given to any hepatitis that occurs from birth up to the 4th month of life and remains etiologically unclassified after clinical and laboratory evaluation. Our purpose was to find symptoms, natural history or factors associated with hepatobiliary disease in infancy and long term prognosis of nonfamilial type of INH. Methods: We followed up 33 cases of INH over a period of 12 years. Features of INH included: a) presence of conjugated hyperbilirubinaemia ?3mg% lasting for more than 2 weeks during the first 4 months of life, b) biochemical and histological features of hepatocellular damage and c) exclusion of all other causes of conjugated hyperbilirubinaemia. Results: Jaundice was developed in all but one child. The liver was palpable in all patients and spleen was present in nineteen patients. Twelve patients with severe anemia (Hb (EN)




Hellenic Society of Gastroenterology (EN)

Annals of Gastroenterology; Volume 14, No 2 (2001) (EN)

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