Perianal Fistulizing Crohn’s disease: imaging modalities and therapeutic challenges

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2009 (EN)
Perianal Fistulizing Crohn’s disease: imaging modalities and therapeutic challenges (EN)

Katsanos, K.H.
Papathanasopoulos, A.A.
Tsianos, E.V.
Christodoulou, D.K.

Perianal involvement in Crohn’s disease is not infrequent. Risk factors for the development of fistulas include a high activity of CD, a fibrostenotic phenotype, genetic markers such as the HLA-DRB1 allele and certain mutations of the genes including NOD2. In perianal CD the treatment should be multidisciplinary. The best outcomes have been achieved when medical and surgical therapies-if needed- are used in conjunction. Therapy of perianal fistulizing CD traditionally includes the use of immunosuppressants and has been significantly modified after the introduction of biologicals. (EN)

Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Gastroenterologiki Company (EN)

2009-10-05


Annals of Gastroenterology (EN)

Annals of Gastroenterology; Volume 22, No 4 (2009); 255 - 262 (EN)



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