Activity monitoring reflects cardiovascular and metabolic variations in COPD patients across GOLD stages II to IV

 
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2013 (EN)
Activity monitoring reflects cardiovascular and metabolic variations in COPD patients across GOLD stages II to IV (EN)

Καλτσάκας, Γεώργιος Σ. (EL)
Κορτιανού, Ελένη Αντ. (EL)
Νάσσης, Γεώργιος (EL)
Λούβαρης, Ζαφείρης (EL)
Βασιλοπούλου, Μαρούλα (EL)

Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας/Σχολή επαγγελμάτων Υγείας και Πρόνοιας/Τμήμα Φυσικοθεραπείας (EL)
Βογιατζής, Ιωάννης (EL)
Κουλούρης, Νικόλαος Γ. (EL)

We investigated whether activity monitoring reliably reflects variations in oxygen transport and utilization during walking in COPD patients. Forty-two patients (14 in each GOLD stage II, III and IV) performed an incremental treadmill protocol to the limit of tolerance. Breath-by-breath gas exchange, central hemodynamic variables and activity monitoring were simultaneously recorded. Physiological variables and accelerometer outputs rose linearly with walking speeds. Strong correlations (r[interquartile range, IQR]) were found between treadmill walking intensity (WI: range 0.8–2.0 m s−2) and oxygen consumption (0.95 [IQR 0.87–0.97]), (range 7.6–15.5 ml kg−1 min−1); minute ventilation (0.95 [IQR 0.86–0.98]), (range 20–37 l min−1); cardiac output (0.89 [IQR 0.73–0.94]), (range 6.8–11.5 l min−1) and arteriovenous oxygen concentration difference (0.84 [IQR 0.76–0.90]), (range 7.7–12.1 ml O2 100 ml−1). Correlations between WI and gas exchange or central hemodynamic parameters were not different across GOLD stages. In conclusion, central hemodynamic, respiratory and muscle metabolic variations during incremental treadmill exercise are tightly associated to changes in walking intensity as recorded by accelerometry across GOLD stages II to IV. Interestingly, the magnitude of these associations is not different across GOLD stages. (EN)

journalArticle

Walking (Sports) (EN)
Καρδιακή παροχή (EN)
Εμμεση θερμιδομετρία (EN)
Περίπατος (EN)
Σωματική δραστηριότητα (EN)
Indirect calorimetry (EN)
Cardiac output (EN)
Activity monitoring (EN)
Παρακολούθηση της δραστηριότητας (EN)
physical activity (EN)
COPD (EN)

ΤΕΙ Αθήνας (EL)
Technological Educational Institute of Athens (EN)

Respiratory Physiology & Neurobiology (EN)

English

2013-12

doi:10.1016/j.resp.2013.08.014

N/A (EN)



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