Azocross-linked poly(acrylic acid) for colonic delivery and adhesion specificity: Synthesis and characterisation

 
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Journal part (EN)
Scientific article (EN)
1998 (EN)
Azocross-linked poly(acrylic acid) for colonic delivery and adhesion specificity: Synthesis and characterisation (EN)
Tsibouklis, J (EN)
Smart, JD (EN)
Kakoulides, EP (EN)
A new synthetic pathway to 4,4'-divinylazobenzene is presented together with a procedure for the copolymerisation of this compound with acrylic acid. The chemical structure of the synthesised series of copolymers is examined in the light of infrared spectroscopy results and nuclear magnetic resonance data. The thermal properties of the materials are assessed using a combination of thermal analysis techniques and their swelling behaviour is evaluated at physiologically relevant buffers designed to mimic the gastrointestinal environment. (C) 1998 Elsevier Science B.V. (EN)
journalArticle (EN)
polymerization (EN)
Azoreduction (EN)
polyacrylic acid (EN)
Biodegradable hydrogels (EN)
Mucoadhesion (EN)
4,4'-Divinylazobenzene (EN)
Drug Carriers (EN)
Colon-specific drug delivery (EN)
Azo Compounds (EN)
Pharmacology & Pharmacy (EN)
Acrylic Resins (EN)
acrylic acid (EN)
priority journal (EN)
Colon (EN)
infrared spectroscopy (EN)
Intestinal Mucosa (EN)
Azopolymers (EN)
nuclear magnetic resonance spectroscopy (EN)
glatiramer (EN)
article (EN)
hydrogel (EN)
benzene derivative (EN)
colon (EN)
drug delivery system (EN)
reduction (EN)
Chemistry, Multidisciplinary (EN)
National Technical University of Athens
Digital Library of National Technical University of Athens | Dspace@NTUA
Κεντρική Βιβλιοθήκη Ε.Μ.Π.
Ιδρυματικό Αποθετήριο
Δημοσιεύσεις μελών Δ.Ε.Π. σε περιοδικά
Journal of Controlled Release (EN)
English
1998 (EN)
http://hdl.handle.net/123456789/12603
0168-3659 (EN)
ISI:000072806100006 (EN)
3 (EN)
300 (EN)
291 (EN)
10.1016/S0168-3659(98)00005-4 (EN)
52 (EN)
ELSEVIER SCIENCE BV (EN)



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