A Diastereoselective Synthesis of Functionalized 3-Pyrazolidinones from Hydrazines, Aromatic Aldehydes and Acylketene

 
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2013 (EN)
A Diastereoselective Synthesis of Functionalized 3-Pyrazolidinones from Hydrazines, Aromatic Aldehydes and Acylketene (EN)

I. Yavari, (EN)

Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας (EL)
I. Yavari, (EN)

A practical microwave-assisted, one-pot method for the construction of 4-acetyl-2-phenyl-5-aryl-3-pyrazolidinones via a tandem reaction between phenylhydrazine, aromatic aldehydes, and but-1-ene-1,3-dione (acylketene), in moderate to good yields, is reported. When methylhydrazine and 4-methylphenylhydrazine hydrochloride were used instead of phenylhydrazine, the reaction led to the formation of 3-oxobutanohydrazide derivatives. (EN)

Πανεπιστήμιο Ιωαννίνων (EL)
University of Ioannina (EN)

Synlett (EN)

2013


Georg Thieme Verlag (EN)



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