Configuration and conformation of a novel uridine analogue: H-1 and C-13 NMR spectra of (5 ' S)-1-[2 '-(2-hydroxyethyl)tetrahydropyran-5 '-yl]-1H-pyrimidine-2,4-dione
Configuration and conformation of a novel uridine analogue: H-1 and C-13 NMR spectra of (5 ' S)-1-[2 '-(2-hydroxyethyl)tetrahydropyran-5 '-yl]-1H-pyrimidine-2,4-dione
(EN)
Balayiannis, G.
(EN)
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών
(EL)
Balayiannis, G.
(EN)
A combination of homo- and heteronuclear 1D and 2D NMR techniques provided the assignment of the H-1 and C-13 resonances of the major component of a reaction product consisting of the two possible diastereomers of (5'S)-1-[2'-(2-hydroxyethyl)tetrahydropyran-5'-yl]-1H-pyrimidine-2,4-dione and showed that the tetrahydropyranyl ring in the major 5S,2'S-isomer adopts the twist conformation. Copyright (C) 2002 John Wiley Sons, Ltd.
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