Kinetic-potentiometric assay of formaldehyde in pharmaceutical and industrial samples, monitored by copper solid ion selective electrode, after its reaction with the copper(II)-bis-(ethylenediamine) complex
Kinetic-potentiometric assay of formaldehyde in pharmaceutical and industrial samples, monitored by copper solid ion selective electrode, after its reaction with the copper(II)-bis-(ethylenediamine) complex
(EN)
Stergiou, D. V.
(EN)
Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας
(EL)
Stergiou, D. V.
(EN)
A kinetic-potentiometric method is described for the quantitative assay of formaldehyde ( HCHO) in pharmaceutical and industrial preparations. It is based on the reaction of HCHO with ( ethylenediamine)-Cu( II)sulfate [Cu(CH2NH2)(2)(H2O)(2)] center dot SO4. The changes in potential, resulting from the release of the Cu( II) cations, are monitored with a Cu( II)-ion selective electrode. The calibration curve for the HCHO is linear in the concentration range 50 - 250 mg L-1, with a limit of detection of 8.5 mg L-1. The method shows very good reproducibility with an RSD of 2.6% for successive injections (n = 5) of 150 mg L-1 HCHO primary solution, while it is interference free. The method was successfully tested in various industrial and pharmaceutical preparations.
(EN)
