Microwave-promoted Suzuki-Miyaura cross-coupling of aryl halides with phenylboronic acid under aerobic conditions catalyzed by a new palladium complex with a thiosemicarbazone ligand

 
This item is provided by the institution :
University of Ioannina
Repository :
Repository of UOI Olympias
see the original item page
in the repository's web site and access all digital files if the item*
share



2006 (EN)
Microwave-promoted Suzuki-Miyaura cross-coupling of aryl halides with phenylboronic acid under aerobic conditions catalyzed by a new palladium complex with a thiosemicarbazone ligand (EN)

Kostas, I. D. (EN)

Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας (EL)
Kostas, I. D. (EN)

A new air- and moisture-stable palladium complex with salicylaldehyde N(4)-hexamethyleneiminylthiosemicarbazone has been synthesized. According to its crystal structure, the metal is bonded to 2 equiv monoanionic thiosemicarbazone moieties in a N,S-bidentate fashion, forming two five-membered chelate rings. while additional intramolecular bonds stabilize the structure. In contrast to other palladium complexes with thiosemicarbazones. this complex was inactive towards the Suzuki-Miyaura coupling under aerobic conditions, by conventional heating. On the other hand. microwave irradiation promoted the effective catalytic activity of the complex for the coupling of aryl bromides and chlorides with phenylboronic acid in DMF/H2O, under aerobic conditions, with turnover numbers of up to 37,000. (c) 2006 Elsevier Ltd. All rights reserved. (EN)

thiosemicarbazone (EN)

Πανεπιστήμιο Ιωαννίνων (EL)
University of Ioannina (EN)

Tetrahedron Lett (EN)

English

2006

<Go to ISI>://000238407500020



*Institutions are responsible for keeping their URLs functional (digital file, item page in repository site)