Novel synthesis of Functionalized Indolizine Derivatives from Huisgen"™s Zwitterions and 1-Methylimidazole/Dichloroketene Adduct

 
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2012 (EN)

Novel synthesis of Functionalized Indolizine Derivatives from Huisgen"™s Zwitterions and 1-Methylimidazole/Dichloroketene Adduct (EN)

I. Yavari, (EN)

Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας (EL)
I. Yavari, (EN)

The reactive zwitterionic intermediates, generated from addition of pyridine derivatives to dialkyl acetylenedicarboxylates, react with 1-methylimidazole/dichloroketene adduct to afford functionalized dialkyl 1-(2,2-dichloroacetyl)indolizine-2,3-dicarboxylates in moderate yields. (EN)

indolizine - acetylenic ester - dichloroacetyl chloride - 1-methylimidazole - N-heterocycle (EN)


Synlett (EN)

English

2012


Georg Thieme Verlag (EN)




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