Synthesis of 1-aroylmethylpyrroles as useful intermediates for further chemical transformation

 
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2008 (EN)
Synthesis of 1-aroylmethylpyrroles as useful intermediates for further chemical transformation (EN)

Karousis, N. (EN)

Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας (EL)
Karousis, N. (EN)

The synthesis of 1-aroylmethylpyrroles from 2-bromo-1-(2-aminophenyl)ethan-1-one and mono-di- or tri-substituted 1H-pyrroles, has been investigated. The reactions take place at r.t. or 80 degrees C in DMF containing potassium carbonate. Reduction of 1-[2-(2-aminophenyl)-2-oxoethyl]-4-bromo-1H-pyrrole-2-carbaldehyde with sodium borohydride gave racemic 1-(2-aminophenyl)-2-[4-bromo-2-(hydroxymethyl)-1H-pyrrol-1-yl]ethanol. (EN)

pyrroles (EN)

Πανεπιστήμιο Ιωαννίνων (EL)
University of Ioannina (EN)

Arkivoc (EN)

English

2008

<Go to ISI>://000254896500014



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