Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants

 
This item is provided by the institution :

Repository :
Repository of UOI Olympias
see the original item page
in the repository's web site and access all digital files if the item*
share



Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants (EN)

Georgiou, D. (EN)

Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας (EL)
Georgiou, D. (EN)

The 1,3-dipolar cycloaddition to N-phenylmaleimide of azomethine ylides, generated in situ from sulfanyl-substituted imines of glycine esters, yields 5H-dihydro-pyrrolo products with syn diastereoselectivity. The syn (major) and anti (minor) products were isolated chromatographically and fully characterized by spectroscopic methods and in two cases also by X-ray analysis. The diastereomeric cycloadducts were tested for their antioxidant activity with good results. (C) 2012 Elsevier Ltd. All rights reserved. (EN)

azomethine ylides (EN)


Bioorganic and Medicinal Chemistry (EN)

English

2012


Elsevier (EN)



*Institutions are responsible for keeping their URLs functional (digital file, item page in repository site)