Ο σακχαρώδης διαβήτης τύπου 1 σε παιδιά και εφήβους. Παράγοντες που συσχετίζονται με τον γλυκαιμικό έλεγχο

 
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2006 (EN)
Ο σακχαρώδης διαβήτης τύπου 1 σε παιδιά και εφήβους. Παράγοντες που συσχετίζονται με τον γλυκαιμικό έλεγχο

Σάιλερ, Ν.
Κίτσιος, Κ.
Καδόγλου, Ν.
Παπαδοπούλου, Μαρία

Aim: To evaluate retrospectively treatment of type 1 diabetes mellitus (DM1) in 99 children and adolescents and to define factors that improve glycemic control. Patients-Methods: We studied 99 children, 43 boys and 56 girls with DM1. Weight, height and body mass index were recorded at every visit. Puberty stage according to Tanner definitions was recorded every 6 months. Glucosylated hemoglobin (HbA1c) was measured 3-4 times/year. From data provided by self monitoring of blood glucose, we calculated the number of daily blood glucose measurements, the number of mild hypoglycemic episodes/week and the number of severe hypoglycemic episodes for the respective period of treatment. Children were treated with two, three or four daily injections of regular and NPH insulin. Results: The mean HbA1c for the whole period of treatment was 8,15±1,39%. The number of mild hypoglycemic episodes/week was 1,6±1,36. The number of severe hypoglycemic episodes/patient/year was 0,39. The mean daily number of blood glucose measurements was 3,0±0,96. The mean annual number of visits to the diabetic clinic was 2,36±0,78. A third injection of regular insulin added before lunch reduced ∏bA1c from 8,78±2,07% to 8,02±1,37% (mean HbA1c decrease - 0,92±1,85%, p<0,001). Children with prepubertal initiation of DM1 improved their glycemic control during adolescence (mean HbA1c: 8,12±1,56% during adolescence vs 8,82±2,2% before puberty, p=0,04). HbA1c was significantly negatively related to the age at the beginning of diabetes (p=0,01), to the daily number of blood glucose measurements (p<0,001) and to the number of mild hypoglycemic episodes/week (p= 0,05). Conclusions: Metabolic control in childhood and adolescence is suboptimal. Intensive insulin treatment and self blood glucose monitoring improve significantly glycemic control

Article / Άρθρο
info:eu-repo/semantics/article

Self monitoring
Υπογλυκαιμία
Εντατικοποιημένη ινσουλινοθεραπεία
Αυτοέλεγχος
Intensive insulin treatment
Hypoglycemia

Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (EL)
Aristotle University of Thessaloniki (EN)

Greek

2006
2016-11-14T10:06:44Z


Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, Σχολή Επιστημών Υγείας, Τμήμα Ιατρικής

Ελληνικά Διαβητολογικά Χρονικά, vol.19 no.4 [2006] p.306-312
urn:ISSN:1106-3270

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info:eu-repo/semantics/openAccess



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