Prolonged benign intrahepatic cholestatic syndrome due to administration of fucidic acid with ticarcillin-clavulanic acid

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Prolonged benign intrahepatic cholestatic syndrome due to administration of fucidic acid with ticarcillin-clavulanic acid (EN)

Tzambouras N.,
Mpaltayiannis G.,
Christodoulou D., .
Tsianos E.V.,
Kitsanou M.,
Katsanos K.H., .

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

2007-03-18


We present the case of a 64-years-old man who was admitted because of 15 days jaundice, white stools, coloured urine, weakness and upper abdominal pain. He had a history of Billroth II operation 35 years ago and before 1 month he was admitted in the Department of Opthalmology because of a trauma in his eye. The laboratory exams revealed mixed hyperbilirubinemia with transaminasemia and elevation of GT and alkaline phosphatase. Because the imagine techniques including ERCP were implying the possibility of a bile duct malignancy a laparotomy was performed which proved negative for malignancy. The Liver biopsy revealed a cholestatic protype with no findings for neoplasia, cirrhosis or other kind of inflammation and the final diagnosis was prolonged delated benign intrahepatic cholestatic syndrome due to the possible synergic action of fucidic acid with ticarcillin-clavulanic acid. These drugs were administered 1 month before during his admission at he Department of Ophthalmology. The biochemical profile became normal 2 months later and the patient lives in excellent health. Key words: jaundice, bilirubin, cholestasis, fucidic acid, ticarcillin-clavulanic acid (EN)


English

Hellenic Society of Gastroenterology (EN)


1792-7463
1108-7471
Annals of Gastroenterology; Volume 13, No 2 (2000) (EN)




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