Gklavas, AntoniosPapaconstantinou, IoannisDellaportas, DionysiosIntestinal resection for Crohn's disease is not curative and postoperative recurrence rates remain high. Early detection of indices associated with recurrence and risk stratification are fundamental for the postoperative management of patients. Early endoscopy at 6-12 months is the "gold standard" procedure, whereas other modalities such as fecal calprotectin and imaging techniques can contribute to the diagnosis of recurrence. The purpose of this review is to summarize current data regarding risk factors correlated with postoperative relapse. Smoking is a well-established, modifiable risk factor. There are sufficient data that correlate penetrating disease, perianal involvement, extensive resections, prior surgery, histological features (plexitis and granulomas), and improper management after resection with high rates for recurrence. The literature provides conflicting data for other possible predictors, such as age, sex, family history of inflammatory bowel disease, location of disease, strictureplasties, blood transfusions, and postoperative complications, necessitating further evidence. On the other hand, surgical factors such as anastomotic configuration, open or laparoscopic approach, and microscopic disease at specimen margins when macroscopic disease is resected, seem not to be related with an increased risk of recurrence. Further recognition of histological features as well as gene-related factors are promising fields for research.Keywords Crohn's disease, recurrence risk factors, postoperative recurrenceAnn Gastroenterol 2017; 30 (6): 598-612text/htmlapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttp://www.annalsgastro.gr/index.php/annalsgastro/article/view/3430engHellenic Society of Gastroenterology1792-74631108-7471Annals of Gastroenterology; Volume 30, No 6 (2017); 598Risk factors for postoperative recurrence of Crohn's disease with emphasis on surgical predictorsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion2017-11-02Δημοσίευση σε περιοδικόPublication in journalΓαστροεντερολογίαGastroenterologyisi -Gastroenterology & Hepatology covers resources on the anatomy, physiology, biochemistry, and pathology of the digestive system. This category includes specific resources on the prognosis and treatment of digestive diseases; stomach ulcers; metabolic, genetic, infectious and chemically induced diseases of the liver; colitis; diseases of the pancreas and diseases of the rectum.Επιστημονικό άρθροScientific articleΒιβλιοκρισία / ΒιβλιοπαρουσίασηBook reviewΕλληνική Γαστροεντερολογική ΕταιρίαGreek Aggregator OpenArchives.gr | National Documentation Centre (EKT)other