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Natural history of grade 1 ascites in patients with liver cirrhosis

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Ελληνική Γαστροεντερολογική Εταιρία   

Αποθετήριο :
Annals of Gastroenterology   

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Natural history of grade 1 ascites in patients with liver cirrhosis (EN)
Triantos, Christos
Assimakopoulos, Stelios F.
Theodorakopoulos, Theodoros
Tsolias, Chrysostomos
Mantaka, Aikaterini
Tselekouni, Paraskevi
Vourli, Georgia
Gogos, Charalampos
Thomopoulos, Konstantinos
Aggeletopoulou, Ioanna
Milionis, Haralampos
Samonakis, Dimitrios N.
Kalafateli, Maria
Kalambokis, Georgios N.
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
2021-01-04
Background No evidence is available on the natural history of grade 1 ascites and its progression to grade 2/3 in patients with liver cirrhosis. The aim of the current study was to address this issue, to assess the development of main comorbid disorders closely related to ascites progression, and to identify the predictive factors for survival in this setting. Methods Consecutive Caucasian cirrhotic patients with grade 1 ascites were retrospectively analyzed. None of patients was under treatment with diuretics at diagnosis. Control groups consisted of 145 cirrhotics with grade 2/3 ascites and 175 cirrhotics without ascites. Results Diuretics were initiated in 58 patients with grade 1 ascites at baseline by the attending physician. At the last follow up, 29 patients had no ascites, 33 patients had grade 1 and 38 patients had grade 2/3 ascites. No variable was found to be an independent predictor of grade 2/3 ascites. Seven patients developed spontaneous bacterial peritonitis while under treatment with diuretics; at that time only 1 patient had grade 1 ascites. The mortality rate was similar among all examined groups. Conclusions This study suggests that the presence of grade 1 ascites does not constitute a precursor of grade 2/3 ascites in patients with cirrhosis. Thus, patients with grade 1 ascites do not require specific treatment with diuretics. Keywords Ascites, grade 1, natural history, liver cirrhosis Ann Gastroenterol 2021; 34 (1): 93-103 (EN)
Αγγλική γλώσσα
Hellenic Society of Gastroenterology (EN)
1792-7463
1108-7471
Annals of Gastroenterology; Volume 34, No 1 (2021); 93 (EN)
Copyright (c) 2021 Annals of Gastroenterology (EN)
Ελληνική Γαστροεντερολογική Εταιρία
Annals of Gastroenterology
Original Articles



*Η εύρυθμη και αδιάλειπτη λειτουργία των διαδικτυακών διευθύνσεων των συλλογών (ψηφιακό αρχείο, καρτέλα τεκμηρίου στο αποθετήριο) είναι αποκλειστική ευθύνη των αντίστοιχων Φορέων περιεχομένου.