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Ocrelizumab-induced inflammatory bowel disease-like illness characterized by esophagitis and colitis

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Hellenic Society of Gastroenterology   

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Annals of Gastroenterology   

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Ocrelizumab-induced inflammatory bowel disease-like illness characterized by esophagitis and colitis (EN)
Barnes, Alex
Klebe, Sonja
Mountifield, Réme
Hall, Lesley-Ann
Hofmann, Dirk
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
2021-05-05
Ocrelizumab is an intravenous anti-CD20 monoclonal antibody, approved for use in primary progressive multiple sclerosis due to its selective depletion of B-lymphocytes. Herein we describe the case of a 56-year-old female who developed odynophagia and bloody diarrhea following treatment with ocrelizumab. This was characterized endoscopically by ulcerations in the esophagus and colon. The patient was treated with high-dose intravenous glucocorticoids with good clinical response. Keywords Ocrelizumab, inflammatory bowel disease, immunotherapy, colitis, esophagitis Ann Gastroenterol 2021; 34 (3): 447-448 (EN)
English
Hellenic Society of Gastroenterology (EN)
1792-7463
1108-7471
Annals of Gastroenterology; Volume 34, No 3 (2021); 447 (EN)
Copyright (c) 2021 Annals of Gastroenterology (EN)
Hellenic Society of Gastroenterology
Annals of Gastroenterology
Case Report



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