Deutsch, MelanieKarapedi, EleniPapadopoulos, NikolaosAloizos, GeorgiosTrifylli, Eleni-MyrtoKoustas, EvangelosAtrial fibrillation (AF) is an increasingly recognized comorbidity in patients with liver cirrhosis, mainly associated with nonalcoholic fatty liver disease and alcohol-associated liver disease, affecting the quality of life and prognosis. On the other hand, cirrhosis is associated with an elevated risk of both thrombosis and bleeding, making the decision about anticoagulation therapy very challenging. Direct-acting oral anticoagulants (DOACs) are approved for patients with non-valvular AF. However, there is limited clinical experience and scientific evidence about their efficacy and safety in liver cirrhosis. This review article investigates the published literatureconcerning the administration of DOACs and traditional antithrombotic agents, such as vitamin K antagonists and heparins, in patients with liver cirrhosis and AF. Keywords Atrial fibrillation, nonalcoholic fatty liver disease, direct-acting oral anticoagulants, vitamin K antagonists Ann Gastroenterol 2022; 35 (6): 557-567text/htmlapplication/pdfhttp://www.annalsgastro.gr/index.php/annalsgastro/article/view/6620engHellenic Society of GastroenterologyCopyright (c) 2022 Annals of Gastroenterology1792-74631108-7471Annals of Gastroenterology; Volume 35, No 6 (2022); 557Anticoagulation in patients with atrial fibrillation and liver cirrhosisinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion2022-11-18Δημοσίευση σε περιοδικόPublication in journalΓαστροεντερολογίαGastroenterologyisi -Gastroenterology & Hepatology covers resources on the anatomy, physiology, biochemistry, and pathology of the digestive system. This category includes specific resources on the prognosis and treatment of digestive diseases; stomach ulcers; metabolic, genetic, infectious and chemically induced diseases of the liver; colitis; diseases of the pancreas and diseases of the rectum.Επιστημονικό άρθροScientific articleΒιβλιοκρισία / ΒιβλιοπαρουσίασηBook reviewΕλληνική Γαστροεντερολογική ΕταιρίαGreek Aggregator OpenArchives.gr | National Documentation Centre (EKT)other