Zacharoulis, DimitriosAdamou, AntonisKapsoritakis, AndreasPapaefthymiou, ApostolisSgantzou, Ioanna KonstantinaSamara, Athina A.Floros, TheodorosDiamantis, AlexandrosVlychou, MariannaRountas, ChristosIoannidis, IoannisFytsilis, FotiosKaragiorgas, GeorgiosBackground Acute cholecystitis (AC) is an emergency commonly managed by a surgical department. The interventional part of the standard treatment algorithm includes laparoscopic or open cholecystectomy. Percutaneous cholecystostomy (PC) under imaging guidance is recommended as the first-line approach in the subset of high-risk patients for perioperative complications, as a bridging therapy to elective surgery or as a definitive solution. The aim of the present study was to evaluate the mortality and morbidity of PC performed under computed tomographic (CT) guidance in patients at high surgical risk. Methods Medical and imaging records from all consecutive patients who underwent a CTPC between 2015 and 2020 were reviewed. Adult patients with a definite indication for CTPC were recruited and mortality 7 and 30 days post-procedure was recorded. Variables potentially affecting those outcomes were retrieved and included in our analysis. Results Eighty-six consecutive patients at high risk for surgical management were identified and included in the present study. Most patients (58.1%) were diagnosed with AC, while 14 (16.3%) had concurrent AC and cholangitis, 13 (15.2%) gallbladder empyema, and 9 (10.4%) hydrops. The 7- and 30-day mortality rates were 16.3% (14/86) and 22.1% (19/86), respectively, and were significantly associated with patients’ hospitalization in the intensive care unit (P<0.05). Other parameters investigated, such as age, sex, diagnosis, catheter diameter, and duration of hospital stay were not significantly associated with our primary outcome. Conclusion PC is a safe alternative to surgery in patients with high perioperative risk, thus providing acceptable mortality rates. Keywords Percutaneous cholecystostomy, computed tomography, acute cholecystitis, high-risk patients Ann Gastroenterol 2022; 35 (6): 668-672text/htmlapplication/pdfhttp://www.annalsgastro.gr/index.php/annalsgastro/article/view/6709engHellenic Society of GastroenterologyCopyright (c) 2022 Annals of Gastroenterology1792-74631108-7471Annals of Gastroenterology; Volume 35, No 6 (2022); 668Computed tomography-guided percutaneous cholecystostomy: a single institution’s 6-year experienceinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion2022-11-18Δημοσίευση σε περιοδικόPublication in journalΓαστροεντερολογίαGastroenterologyisi -Gastroenterology & Hepatology covers resources on the anatomy, physiology, biochemistry, and pathology of the digestive system. This category includes specific resources on the prognosis and treatment of digestive diseases; stomach ulcers; metabolic, genetic, infectious and chemically induced diseases of the liver; colitis; diseases of the pancreas and diseases of the rectum.Επιστημονικό άρθροScientific articleΕλληνική Γαστροεντερολογική ΕταιρίαGreek Aggregator OpenArchives.gr | National Documentation Centre (EKT)other