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Evaluation of parameters influencing the quality of colon preparation with a split-dose regimen of sulfate salts

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Ελληνική Γαστροεντερολογική Εταιρία   

Αποθετήριο :
Annals of Gastroenterology   

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Evaluation of parameters influencing the quality of colon preparation with a split-dose regimen of sulfate salts (EN)
Tzakri, Mary
Koumentakis, Charalampos
Papathanasiou, Evgenia
Pardalis, Pavlos
Pantelakis, Emmanouil
Axiaris, Georgios
Leonidakis, Georgios
Michopoulos, Spyridon
Ioannou, Alexandros
Vasilieva, Larisa
Zampeli, Evanthia
Baxevanis, Panagiotis
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
2024-03-19
Background Bowel cleansing is an important factor for the quality of colonoscopy. We aimed to evaluate the efficacy of split-dose oral sulfate salts on bowel preparation and to determine parameters influencing the quality of bowel cleaning. Method Consecutive adults who completed their preparation for colonoscopy with a regimen of sulfate salts were enrolled. Results Of the 446 patients, 11 were excluded from the analysis. Among the 435 patients, 257 (59.1%) were female, mean age was 62.0±11.6 years and median body mass index (BMI) 26.1 kg/m2 (interquartile range [IQR] 23.8-29.4). Indications for colonoscopy were screening 155 (35.6%), surveillance 102 (23.5%), or other 178 (40.9%). The median time between the end of second dose of the preparation regimen and colonoscopy initiation was 5:15 h (IQR 4:30-6:00, min: 2:20, max: 12:20). Minor adverse events were reported in 62 (14.3%) patients. BBPS=9 was observed in 279 (64.14%) patients. Segmental BBPS=3 was achieved in 387 (88.97%), 346 (79.54%) and 289 (66.44%) patients (P<0.001) in the descending, transverse and ascending colon, respectively. Multivariate analysis revealed that BMI (odds ratio [OR] 1.05, 95% confidence interval [CI] 1-1.1) and time between the end of the second laxative dose and colonoscopy initiation (OR 1.25, 95%CI 1.08-1.45) were associated with poorer bowelpreparation. Conclusions A split dose of oral sulfate salts is an efficacious and well tolerated regimen. Obesity and a longer time interval between the end of the second dose and colonoscopy initiation negatively influence bowel cleanliness. Keywords Colonoscopy, bowel preparation, oral triphosphate Ann Gastroenterol 2024; 37 (2): 172-178 (EN)
Αγγλική γλώσσα
Hellenic Society of Gastroenterology (EN)
1792-7463
1108-7471
Annals of Gastroenterology; Volume 37, No 2 (2024); 172 (EN)
Copyright (c) 2024 Annals of Gastroenterology (EN)
Ελληνική Γαστροεντερολογική Εταιρία
Annals of Gastroenterology
Original Articles



*Η εύρυθμη και αδιάλειπτη λειτουργία των διαδικτυακών διευθύνσεων των συλλογών (ψηφιακό αρχείο, καρτέλα τεκμηρίου στο αποθετήριο) είναι αποκλειστική ευθύνη των αντίστοιχων Φορέων περιεχομένου.