Problems and challenges in the design of Irritable Bowel Syndrome clinical trials. Focusing on the future with the experience from the past

 
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2007 (EN)
Problems and challenges in the design of Irritable Bowel Syndrome clinical trials. Focusing on the future with the experience from the past (EN)

., K. Triantafyllou

SUMMARY Irritable Bowel Syndrome (IBS) is a common chronic disorder that is associated with significant disability and health costs. Drug development for this disorder is complex for a variety of reasons. A review of the literature concludes that there are few studies, which offer convincing evidence of effectiveness in treating IBS symptoms. Future trials must be double blind, placebo controlled, use internationally approved diagnostic criteria and describe the randomisation method. Clear, well-defined outcome measures are necessary as well. Key words: Irritable bowel syndrome, drug development diagnostic criteria, side effects (EN)

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Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Society of Gastroenterology (EN)

2007-03-19


Hellenic Society of Gastroenterology (EN)

1792-7463
1108-7471
Annals of Gastroenterology; Volume 15, No 3 (2002) (EN)



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