Stamatelatos, Ion E.Rabochová, MichaelaKalef-Ezra, John A.Klupák, VitKalamara, AntigoniGeorgiou, SofiaTheodossiou, TheodossisStefanopoulos, Konstantinos L.Šoltés, JaroslavVinš, MiroslavThe HK-1 neutron beam line at the LVR-15 reactor in ÚJV Řež, Czech Republic, was used for in vitro cell studies carried out in the framework of the FRINGE project, aiming on the development of a novel neutron capture therapy technique using Gd containing compounds. The neutron fluence rate close the HK-1 beam exit was experimentally assessed. Neutron fluence rate data were combined with Monte Carlo simulations performed using the MCNP 6.1 code, to model a well-type vial containing a thin layer of cells, with and without Gd, as well as the supporting media. Aim of the study was to evaluate the energy deposited by the neutrons in the cell monolayers and delineate the contribution of the various dose components in an attempt to interpretate the findings of the in vitro studies.application/pdfhttps://eproceedings.epublishing.ekt.gr/index.php/hnps/article/view/628510.12681/hnpsanp.6285engHellenic Nuclear Physics Society (HNPS)http://creativecommons.org/licenses/by-nc-nd/4.0Πνευματική ιδιοκτησία (c) 2024 Antigoni Kalamara, Sofia Georgiou, Konstantinos L. Stefanopoulos, Ion E. Stamatelatos, John A. Kalef-Ezra, Miroslav Vinš, Vit Klupák, Michaela Rabochová, Jaroslav Šoltés, Theodossis TheodossiouAnnual Symposium of the Hellenic Nuclear Physics Society2654-00882654-007XAnnual Symposium of the Hellenic Nuclear Physics Society; Τόμ. 30 (2024); 207-210HNPS Advances in Nuclear Physics; Vol. 30 (2024): HNPS2023; 207-210cancer therapyMonte Carlo simulationsdosimetryneutronNeutron dosimetry at HK-1 beam line of LVR-15 reactor for biomedical sample irradiationsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion2024-07-31Πυρηνική φυσικήNuclear Physicsisi - Physics, Nuclear includes resources on the study of nuclear structure, decay, radioactivity, reactions, and scattering. Resources in this category focus on low-energy physics. High-energy physics is covered in the PHYSICS, PARTICLES & FIELDS category.Άρθρο συνεδρίουConference articleΕπιστημονικό άρθροScientific articleHellenic Nuclear Physics SocietyGreek Aggregator OpenArchives.gr | National Documentation Centre (EKT)