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Study of aminoglycoside-nucleic acid interactions by an HPLC method

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Technological Educational Institute of Athens   

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Study of aminoglycoside-nucleic acid interactions by an HPLC method (EN)
Κωνσταντίνου-Κόκοτου, Βιολέτα (EL)
Κοκοτός, Γιώργος (EL)
Καρίκας, Γεώργιος-Αλβέρτος (EL)
journalArticle
2015-05-09T19:50:49Z
2015-05-09
2001-04-23
Bioorganic & Medicinal Chemistry Letters (EN)
The interactions of a number of aminoglycoside antibiotics with tRNA and DNA were studied by an HPLC method. based on tRNA and DNA peak size exclusion. Among the compounds studied (deoxystreptamine, neamine, neomycin B, kanamycin A, gentamicin A, netilmicin, streptomycin, and the synthetic neamine analogue BKN3), neomycin B and the synthetic analogue of neamine were proved to be the most potent binders. (EN)
νουκλεϊκά οξέα
http://id.loc.gov/authorities/subjects/sh85093148
aminoglycoside antibiotics
http://skos.um.es/unescothes/C00568
μέθοδος HPLC
HPLC method
Chemistry
http://id.loc.gov/authorities/subjects/sh85100603
Nucleic acids--Synthesis
Χημεία
Pharmacy
Φαρμακευτική
αντιβιοτικά
http://lod.nal.usda.gov/148694
**N/A**-Χημεία
**N/A**-Φαρμακευτική
Elsevier (EN)
Τεχνολογικό Εκπαιδευτικό Ίδρυμα Αθήνας. Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Ιατρικών Εργαστηρίων (EL)
http://www.sciencedirect.com/science/article/pii/S0960894X01001159
Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ηνωμένες Πολιτείες
http://creativecommons.org/licenses/by-nc-nd/3.0/us/
campus
Technological Educational Institute of Athens
Ypatia - Institutional Repository
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