Associations of placental weight with maternal and cord blood hormones

 
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2013 (EN)
Associations of placental weight with maternal and cord blood hormones (EL)

Λάγιου, Αρετή (EL)
Λάγιου, Παγώνα Δ. (1967-) (EL)
Σαμόλη, Ευαγγελία (EL)
Hsieh, Chung-Cheng (EN)
Xu, Biao (EN)

Σχολή Επαγγελμάτων Υγείας και Πρόνοιας. Τμήμα Δημόσιας Υγείας και Κοινοτικής Υγείας. Κατεύθυνση Δημόσιας Υγείας (Δημόσιας Υγιεινής) (EL)
Chie, Lucy (EL)
Τριχόπουλος, Δημήτρης Βασ. (1938-2014) (EL)
Onoyama, Sagano (EN)
Adami, Hans-Olov (EN)
Williams, Michelle A. (EN)
Yu, Guo-Pei (EN)
Vatten, Lars J. (EN)

Prospective study of 167 normal singleton pregnancies in Boston, USA and 256 in Shanghai, China. Maternal hormone levels at the 27th gestational week were available for all pregnancies. Cord blood measurements were available for 86 pregnancies in Boston and 104 in Shanghai. Pearson partial correlation coefficients of log-transformed hormone levels with placental weight were calculated. Results Maternal levels of estriol, testosterone, and progesterone (P < .05) were positively associated with placental weight. There was no such evidence for adiponectin, prolactin, and insulin-like growth factor (IGF)-I. Cord blood steroids tended to be inversely associated with placental weight, the results being statistically significant for testosterone (P < .05). There was a marginally significant positive association of cord blood IGF-I with placental weight. Reported results were adjusted for study center. Conclusions Placental weight appears to be positively correlated with maternal steroids. Its correlation with cord blood steroids, however, appears inverse, compatible with negative feedback mechanisms. There is also a suggestion for placental weight to be positively associated with cord blood IGF-I. (EN)

journalArticle

Ινσουλίνη- αυξητικός παράγοντας (EN)
Ορμόνες (EN)
Ενδομήτρια ανάπτυξη (EN)
Placenta (EN)
Intrauterine growth (EN)
insulin-like growth factor I (EN)
Πλακούντας (EN)
Hormones (EN)

ΤΕΙ Αθήνας (EL)
Technological Educational Institute of Athens (EN)

Annals of Epidemiology (EN)

English

2013-11

doi:10.1016/j.annepidem.2013.08.003

N/A (EN)



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