The purpose of this review on floating and swellable drug delivery systems is to
compile the recent literature with special focus on the principal mechanism of
floatation to achieve gastric retention. The review also aims to discuss various
parameters affecting the behavior of floating and swelling multiparticulate in oral
dosage form summarizes the in vitro techniques, in vivo studies to evaluate the
performance and application of floating and swellable systems, and applications of
these systems. These systems are useful to several problems encountered during the
development of a pharmaceutical dosage form. From the formulation and
technological point of view, the floating and swellable drug delivery systems are
considerably easy and logical approach. An attempt has been made in this review
article to introduce the scientists to the current technological developments in floating
and swellable drug delivery system.
(EN)
