Pantelis, ESakelliou, LBaltas, DPapagiannis, PKaraiskos, PAngelopoulos, AKouwenhoven, EA new microSelectron pulsed dose rate source has been designed, containing two active pellets instead of one inactive and one active pellet contained in the old design, to facilitate the incorporation of higher activity up to 74 GBq (2 Ci). In this work, Monte Carlo simulation is used to derive full dosimetric data following the AAPM TG-43 formalism, as well as the dose rate. per unit air kerma strength data in Cartesian, "away and along" coordinates for both source designs. The calculated dose rate constant of the new PDR source design was found equal to Lambda=(1.121 +/- 0.006) cGyh(-1)U(-1) compared to Lambda=(1.124+/-0.006) cGy h(-1)U(-1) forthe old design. Radial dose functions of the two sources calculated using the point source approximated geometry factors were found in close agreement (within 1%) except for radial distances under 2 mm. At polar angles close to the longitudinal source axis at the sources' distal end, the new design presents increased anisotropy (up to 10%) compared to the old one due to its longer active core. At polar angles close to the longitudinal source axis at the sources' drive wire end however, the old design presents increased anisotropy (up to 18%) due to attenuation of emitted photons through the inactive Ir pellet. These differences, also present in "away and along" dose rate results, necessitate the replacement of treatment planning input data for the new microSelectron pulsed dose rate source. (C) 2003 American Association of Physicists in Medicine.http://hdl.handle.net/123456789/154061160094-240510.1118/1.1524168ISI:000180493600002930engAMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICSMedical PhysicsdosimetryHumansanisotropyiridium 192airIridium RadioisotopesMonte CarloSensitivity and SpecificityRadiometryBrachytherapyDosimetrybrachytherapypriority journalradiation doseRadiopharmaceuticalsRadiotherapy Planning, Computer-Assisted192IrPDRQuality ControlRadiotherapy DosageMonte Carlo methoddose calculationmathematical analysiswaterarticlephotonphantompulsed dose rate brachytherapyAnisotropygeometryPhantoms, ImagingMonte Carlo MethodMonte Carlo dosimetry of a new 192Ir pulsed dose rate brachytherapy sourcejournalArticle2003Ραδιολογία, Πυρηνική ιατρική και ΑπεικονιστικήRadiology, Nuclear Medicine and Imagingisi - Radiology, Nuclear Medicine & Medical Imaging covers resources on radiation research in biology and biophysics. Resources in this category focus on interventional radiology, investigative radiology, neuroradiology, radiotherapy, and oncology. Nuclear Medicine resources are concerned with the diagnostic, therapeutic, and investigative use of radionuclides. Medical Imaging resources are concerned with computerized medical imaging and graphics.Δημοσίευση σε περιοδικόPublication in journalΕπιστημονικό άρθροScientific articleΕθνικό Μετσόβιο ΠολυτεχνείοGreek Aggregator OpenArchives.gr | National Documentation Centre (EKT)other