Synthesis and in vitro cytotoxicity of aminocoumarin platinum(II) complexes
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Kokotos, G.
(EN)
Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας
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Kokotos, G.
(EN)
A number of cis-dichloro[bis(aminocoumarin)]platinum complexes have been synthesized and evaluated for their in vitro cytotoxicity against Caco-2T cells. The complex with 7-amino-4-trifluoromethylcoumarin as ligand has been found to be the most active (IC50 10 mu g/ml) in this study. (C) 1997 Elsevier Science Ltd.
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