Synthesis of beta,gamma-unsaturated primary amides from alpha,beta-unsaturated acids and investigation of the mechanism

 
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2011 (EN)
Synthesis of beta,gamma-unsaturated primary amides from alpha,beta-unsaturated acids and investigation of the mechanism (EN)

Theodorou, V. (EN)

Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας (EL)
Theodorou, V. (EN)

alpha,beta-Unsaturated acids, through their acid chlorides, react with tritylamine in the presence of triethylamine under mild conditions, to afford in high yield and high regioselectivity the corresponding beta,gamma-unsaturated tritylamides. Detritylation with TFA generates quantitatively beta,gamma-unsaturated primary amides. An investigation of this deconjugative isomerization was performed. (C) 2011 Elsevier Ltd. All rights reserved. (EN)

beta,gamma-unsaturated n-tritylamides (EN)

Πανεπιστήμιο Ιωαννίνων (EL)
University of Ioannina (EN)

Tetrahedron (EN)

English

2011

<Go to ISI>://000293109400015

Elsevier (EN)



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