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1  -  9   to   9   items

     
    Εκλεκτικοί αναστολείς πρωτεϊνικών κινασών: σχεδιασμός, σύνθεση και μοριακή μοντελοποίηση νέων, ευρέως τροποποιημένων αναλόγων της Ιματινίβης: εισαγωγή των δομών της Χρωμόνης και της Κουμαρίνης Selective protein kinase inhibitors: design, synthesis, and molecular modeling of new, widely modified Imatinib analogues: introduction of Chromone and Coumarin structures
    Creator: Gogou, Marina, Γώγου, Μαρίνα
    Item type: PhD thesis
    Scientific field: Organic Chemistry
    Υear: 2022
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Ορθολογικός σχεδιασμός και σύνθεση διαγνωστικών και θεραπογνωστικών ενώσεων που φθορίζουν στην περιοχή του εγγύς υπερύθρου και στοχεύουν το μικροπεριβάλλον των καρκινικών κυττάρων Rational design and synthesis of diagnostic and theragnostic probes that emit in the near infrared region and target tumor microenvironment
    Creator: Diamantis, Dimitrios, Διαμαντής, Δημήτριος
    Item type: PhD thesis
    Scientific field: Applied Chemistry, Organic Chemistry
    Υear: 2022
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Σχεδιασμός, σύνθεση και βιολογικός έλεγχος νέων βιοδραστικών ενώσεων, αναλόγων της Νιλοτινίβης (Νilotinib) και της Ιματινίβης (Ιmatinib) ως αναστολέων πρωτεϊνικών κινασών και της πολυμεράσης της πόλυ­(ΑDP­ριβόζης) (PARP)­: ανάπτυξη νέας βελτιωμένης ολικής σύνθεσης του αναστολέα Rucaparib Design, synthesis and biological evaluation of new biodrastic compounds, analogues of Nilotinib and Imatinib, as inhibitors of protein kinases and polymerase of poly-(ADP-riboze) (PARP): development of new improved total synthesis of Rucaparib inhibitor
    Creator: Ντέμου, Νικολέτα, Ntemou, Nikoleta
    Item type: PhD thesis
    Scientific field: Chemical sciences
    Υear: 2020
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Ανάπτυξη καινοτόμων διαγνωστικών, θεραπευτικών και θεραπογνωστικών μορίων ανταποκρινόμενων στο μικροπεριβάλλον των καρκινικών κυττάρων με στόχο την εξατομικευμένη θεραπεία Development of novel therapeutic, diagnostic and theragnostic agents, that are responsive to the microenvironment of cancer cells with the aiming personalized treatment
    Creator: Tsiailanis, Antonios, Τσιαϊλάνης, Αντώνιος
    Item type: PhD thesis
    Scientific field: Chemical sciences
    Υear: 2023
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
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    Ανάπτυξη καινοτόμων μεθοδολογιών για την αξιοποίηση φυτοχημικών από φαρμακευτικά φυτά της Ηπείρου, με στόχο την αναστολή της δράσης των ενζύμων ελαστάσης, υαλουρονιδάσης και τυροσινάσης, με σκοπό την ανάπτυξη καλλυντικού προϊόντος Development of novel methodologies for the utilization of phytochemicals derived from medicinal plants which are grown in the region of Epirus, targeting the inhibition of the enzymes elastase, hyaluronidase and tyrosinase, in order to develop cosmetic products
    Creator: Παπαεμμανουήλ, Χριστίνα, Papaemmanouil, Christina
    Item type: PhD thesis
    Scientific field: Analytical Chemistry, Biochemistry and Molecular Biology
    Υear: 2021
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Σχεδιασμός, σύνθεση και βιολογικός έλεγχος νέων αναλόγων του φαρμακευτικού σκευάσματος Lenvatinib ως εν δυνάμει αναστολέων του υποδοχέα του αγγειακού ενδοθηλιακού αυξητικού παράγοντα 2 (VEGFR2) και βελτιστοποίηση της συνθετικής του πορείας Design, synthesis and biological control of new analogues of the pharmaceutical formulation Lenvatinib as potential inhibitors of the vascular endothelial growth factor receptor 2 (VEGFR2) and optimization of its synthetic pathway
    Creator: Alagiannis, Michalis, Αλαγιάννης, Μιχάλης
    Item type: PhD thesis
    Scientific field: Organic Chemistry
    Υear: 2022
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Μοριακός σχεδιασμός, σύνθεση και βιολογική δράση εν δυνάμει αναστολέων πρωτεϊνικών κινασών Molecular design, synthesis and biological activity of potential protein kinase inhibitors
    Creator: Μπρέντας, Αλέξιος, Brentas, Alexios
    Item type: PhD thesis
    Scientific field: Drug Discovery, Organic Chemistry
    Υear: 2023
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Δομικές μελέτες ενώσεων βιολογικού ενδιαφέροντος με τη συνδυαστική χρήση NMR και θεωρητικών υπολογισμών Structural studies of biological interest compounds with the combined use of NMR and theoretical calculations
    Creator: Βενιανάκης, Θεμιστοκλής, Venianakis, Themistoklis
    Item type: PhD thesis
    Scientific field: Organic Chemistry
    Υear: 2023
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

    Λογικός σχεδιασμός, σύνθεση και βιολογική αξιολόγηση "έξυπνων μοριακών συσκευών", θεραπευτικών και θεραπογνωστικών μορίων που ανιχνεύουν, στοχεύουν και θεραπεύουν τον καρκίνο Rational design, synthesis and biological evaluation of «smart molecular devices», therapeutic and theragnostic compounds to detect, target and respond to the tumor microenvironment
    Creator: Χατζηγιάννης, Χρήστος, Chatzigiannis, Christos
    Item type: PhD thesis
    Scientific field: Organic Chemistry
    Υear: 2023
    Language: Greek
    School/department/institute: University of Ioannina ▶ School of Science ▶ Department of Chemistry ▶ Section of Organic Chemistry and Biochemistry ▶ Laboratory of Organic Chemistry (1976 - ...)
    Institution: National Documentation Centre (EKT)
    Collection : National Archive of PhD Theses  | ΕΚΤ NA.Ph.D.
    RDF

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