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Understanding the microbiome: a primer on the role of the microbiome in colorectal neoplasia

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Understanding the microbiome: a primer on the role of the microbiome in colorectal neoplasia (EN)
Watson, Katherine M.
Tsikitis, Vassiliki Liana
Gaulke, Christopher A.
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
2020-05-08
Colorectal cancer is a leading cause of cancer-related death internationally, with mounting evidence pointing to the role of the microbiome in adenoma and cancer development. This article aims to provide clinicians with a foundation for understanding the field of research into the microbiome. We also illustrate the various ways in which the microbiota have been linked to colorectal cancer, with a specific focus on microbiota with identified virulence factors, and also on the ways that byproducts of microbiota metabolism may result in oncogenesis. We also review strategies for manipulating the microbiome for therapeutic effects. Keywords Microbiome, colorectal cancer, colorectal adenomas Ann Gastroenterol 2020; 33 (3): 223-236 (EN)
English
Hellenic Society of Gastroenterology (EN)
1792-7463
1108-7471
Annals of Gastroenterology; Volume 33, No 3 (2020); 223 (EN)
Copyright (c) 2020 Annals of Gastroenterology (EN)
Hellenic Society of Gastroenterology
Annals of Gastroenterology
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